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Plant hardware

WIDE RANGE OF PLANT EQUIPMENT SOLUTIONS TO SATISFY CUSTOMERS’ REQUIREMENTS

Dipharma’s customers can count on an experienced team of highly trained technical personnel, as well as a wide range of available equipment solutions to satisfy their requirements. Our four production sites, with a total reactor capacity of 600 m3, have been regularly inspected by US FDA and European agencies for more than 30 years, and all operate in accordance with Good Manufacturing Practices (cGMP), and of course are compliant with safety and environmental care principles.

Plant hardware of Dipharma - Baranzate
Overview of Dipharma - Baranzate

Reactor volume about 90 m3 (range 0.5-12 m3, SS/glass lined)
Operating temperature range -20°C to +150°C
Pressure rating from full vacuum up to 5 bar
Specific technologies dimethyl sulphate, Grignard reactions and jet mill micronizers
Process water plant deionised water (ion exchange resins)
Finishing areas centrifuges, (SS/halar lined), driers and mills in clean-rooms with filtered air by HVAC system


Plant hardware of Dipharma - Caronno Pertusella

Overview of Dipharma  - Caronno Pertusella

Reactor volume about 230 m3 (range 0,8-12 m3, SS/glass lined)
Operating temperature range -15°C to +180°C
Pressure rating from full vacuum up to 5 bar
Specific technologies hydrazine, hydrogenation (up to 6 bar), halogenation, dissolving metals reduction and chlorine
Process water plant deionized water (ion exchange resins)
Finishing areas centrifuges, driers and sleve in clean-rooms with filtered air by HVAC system
Small production plant consisting of - glass-lined and stainless steel reactors
- stainless steel centrifuge enclosed in a dedicated clean room with filtered air system
- distillation unit complete of 180 m3 stainless steel storage tanks used for the recovery of solvents


Plant hardware of Dipharma - Mereto di Tomba

Overview of Dipharma  - Mereto di Tomba

Reactor volume about 200 m3 (range 1-10 m3, SS/glass lined)
Operating temperature range -10°C to +180°C (some of them up to +220/280°C)
Pressure rating from full vacuum up to 6 bar
Specific technologies heterogeneous hydrogenation (up to 40 bar), nitration (continuous and batch), azidation, chlorination, nitroalkanes
Process water plant reverse osmosis
Finishing areas centrifuges (SS/halar lined), driers (SS/Hastelloy), blender and mill in clean-rooms with filtered air by HVAC system
Dedicated pilot plant - glass-lined and stainless steel reactors (from  200 lt to 1000 lt)
- anti acid centrifuge enclosed in a dedicated clean room
- drier enclosed in a dedicated clean room